The PRRX1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Prrx1. This antibody recognizes Human, Mouse, and Rat antigen. The PRRX1 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
The paired related homeobox protein 1 (PRRX1) is a paired-type DNA-binding homeodomain that plays an important role as a key switch for neural cell lineage determination and is essential for development (1,2). PRRX1 is expressed in a number of undifferentiated mesenchymal cells in mouse embryos and adults (3). Mice with a disrupted PRRX1 gene show perinatal death with craniofacial and limb malformations (4). Low PRRX1 expression levels were significantly associated with metastasis and poor prognosis of breast and colorectal cancer (5)